ΔΟΚΙΜΑΣΙΑΙ ΑΙΜΟΣΤΑΤΙΚΟΥ ΜΗΧΑΝΙΣΜΟΥ ΕΠΙ ΑΣΘΕΝΩΝ ΜΕΤΑ ΥΠΕΡΛΙΠΙΔΑΙΜΙΑΣ ΤΥΠΟΥ IV

Abstract

PLATELET FUNCTIONS BLOOD COAGULATION AND FIBRINOLYSIS WERE STUDIED IN TWELVE PATIENTS WITH TYPE IV HYPERLIPIDAEMIA.THE PLATELET COUNT WAS NORMAL IN ALL SUBJECTS.THE PLATELET FUNCTION TESTED BY AGGREGATION METHOD (TURBIDOMETRIC TECHNIQUE) USING ADP.ADRENALIN AND COLLAGEN AS AGGREGATION INDUCING AGENTS, PLATELETADHESIVESS (SALZMAN'S TECHNIQUE).ADP-RELEASE (AGGREGATION METHOD), PLATELET FACTOR-3 AVAILABILITY AND CLOT RETRACTION WAS NORMAL.THE BLOOD COAGULATION SCREENED BY QUICK TIME,THROMBIN TIME AND PARTIAL THROMBOPLASTIN TIME WAS NORMAL.ALSO THE PLASMA LEVELS OF FACTOR VIII AND ANTITHROMBIN III WERE WITHIN NORMAL RANGE,WHILE THE FIBRINOGEN LEVEL WAS SLIGHTLY INCREASED. THE FIBRINOLYTIC ACTIVITY TESTED BY THE EUGLOBULIN CLOLYSIS TIME IN REST OR AFTER VENOUS OCCLUSION WAS FOUND REDUCED.THE FIBRINOGEN/FIBRIN DEGRADATION PRODUCTS AND THE PLASMINOGEN WERE NORMAL.