Optimization of neonatal ventilation

Abstract

Introduction: A large number of methods and techniques of mechanical ventilation and respiratory support in general are now available for neonates. Neonates, especially premature ones, are at high risk of developing respiratory muscle fatigue, due to reduced oxidative capacity of their respiratory muscles. It is important to identify the ventilatory support techniques with the lowest work of breathing in neonates to ensure their fastest weaning from any ventilatory support. The integral of the transdiaphragmatic pressure over the inspiratory time, the diaphragmatic pressure-time product (PTPdi), reflects the energetic expenditure of the diaphragm and has been used as a measure of the work of breathing. Aim: The aim of this thesis was to compare the imposed work of breathing by measurement of the diaphragmatic pressure-time product (PTPdi) in premature infants, supported by mechanical respiratory support methods commonly used in Neonatal Intensive Care Units (NICUs), in order to determi ...
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DOI
10.12681/eadd/54534
Handle URL
http://hdl.handle.net/10442/hedi/54534
ND
54534
Alternative title
Βελτιστοποίηση της αναπνευστικής υποστήριξης στη νεογνική περίοδο
Author
Vervenioti, Angeliki (Father's name: Georgios)
Date
2023
Degree Grantor
University of Patras
Committee members
Καρατζά Αγγελική
Χρύσης Διονύσιος
Σινωπίδης Ξενοφών
Βαρβαρήγου Αναστασία
Ανθρακόπουλος Μιχαήλ
Φούζας Σωτήριος
Δάσιος Θεόδωρος
Discipline
Medical and Health SciencesClinical Medicine ➨ Pediatrics, Perinatology and Child Health
Keywords
Preterm infant; Ventilation; Optimization
Country
Greece
Language
Greek
Description
im., tbls., fig., ch.
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